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As expected, glucagon infusion caused an increase in glucose which was largely neutralised by co-infusion with GLP-1

It is best to use a new, sterile needle for each injection

8 Vaginal dryness and irritation Painful intercourse due to tissue thinning and reduced lubrication Urinary urgency, frequency, or stress incontinence Cognitive & Psychological Symptoms Up to 70% of women report cognitive or emotional changes during menopause

A landmark study out of Mayo Clinic, published in The Lancet Obstetrics, Gynaecology & Women's Health in January 2026, tracked 120 postmenopausal women on tirzepatide for a year or more